Nottingham, UK
Formulation Development, Spray Drying & Oral Solid Dose Development & Manufacturing
Codis Nottingham is a specialist pharmaceutical development and manufacturing facility with more than two decades of experience in formulation development, spray drying, analytical services, clinical supply and oral solid dose manufacturing. The site combines deep scientific expertise with integrated development and manufacturing capabilities to support complex drug products from early development through clinical supply and small-scale commercial production.
Capabilities at a Glance
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Materials Characterization
The Nottingham facility provides integrated materials characterization to support formulation selection, spray drying process development, and oral solid dose performance. Physical and solid-state analytical capabilities help teams understand critical material properties, evaluate spray-dried intermediates, and make informed development decisions from early feasibility through clinical manufacturing and scale-up.
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Formulation Development & Spray Drying
The Nottingham facility provides formulation development and development-scale spray drying for poorly soluble compounds and amorphous solid dispersions (ASDs). Integrated formulation, process, and analytical expertise supports programs from initial feasibility and formulation screening through process optimization, clinical manufacturing, and preparation for technology transfer and scale-up.
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Oral Solid Dose Development & Manufacturing
Co-located OSD capabilities provide an integrated route from spray-dried intermediate to finished dosage form. The site supports oral solid dose development, clinical supply manufacturing, and small-scale commercial production, bringing formulation, analytical services, and manufacturing together at a single facility.
Codis Is Creating a New Standard in Integrated Spray Drying
Discover how Codis combines formulation science, particle engineering, development-scale spray drying, oral solid dose manufacturing, and commercial-scale production to support drug products throughout the development lifecycle.
Together, Nottingham and Haverhill provide an integrated UK pathway from early formulation development and clinical supply through technology transfer and commercial-scale spray drying.
A Legacy of Scientific Expertise, Now Part of Codis
For more than 20 years, the Nottingham facility has supported pharmaceutical companies with materials characterization, formulation development, development-scale spray drying, analytical services, clinical supply, and oral solid dose solutions.
Now part of Codis, the site strengthens our expertise in bioavailability enhancement and particle engineering while expanding our capabilities in clinical supply and small-scale commercial OSD manufacturing. Its experienced scientific and technical teams bring established development knowledge to the Codis network.
Transferring a spray drying process from development to commercial-scale manufacturing is a critical stage in the product lifecycle. Changes in equipment, operating conditions, and batch scale can affect process performance and the properties of the resulting material.
Codis brings together development and clinical manufacturing at Nottingham with commercial-scale spray drying at Haverhill. Integrated technical teams support formulation development, process understanding, analytical method transfer, technology transfer, and scale-up planning within a single organization and quality system.
This connected approach provides a clear route through:
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Amorphous Solid Dispersion Development
Codis develops spray-dried amorphous solid dispersions to improve the oral bioavailability of poorly soluble compounds. The Nottingham team applies formulation, process, and analytical expertise to evaluate drug-polymer systems, develop suitable spray drying processes, and characterize the resulting material.
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Development-Scale Spray Drying
Development-scale spray drying capabilities support feasibility studies, formulation screening, process development and optimization, and the manufacture of material for clinical programs. Development data and process knowledge help prepare programs for subsequent technology transfer and scale-up.
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Oral Solid Dose Development
The site’s oral solid dose expertise connects the development of spray-dried intermediates with finished dosage forms. Formulation and process development activities consider tablet and capsule performance, manufacturability, and stability.
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Clinical and Small Scale Commercial Manufacturing
Integrated development, analytical, and manufacturing capabilities support clinical supply and small-scale commercial manufacture at the site. Program-specific requirements are defined according to product stage, intended use, and target markets.
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Analytical Services
Analytical development and characterization are integrated throughout formulation and process development. Capabilities support analytical method development and transfer, product characterization, stability studies, quality control testing, and product release requirements.
Quality, Compliance & Regulatory Excellence
The Nottingham facility operates within Codis’s established quality framework, with quality, development, analytical, and manufacturing teams working together throughout program delivery.
Project requirements are defined according to the development phase, intended use of the material, target markets, and applicable regulatory expectations. This includes appropriate specifications, analytical methods, stability requirements, manufacturing controls, documentation, and release arrangements.
Codis is committed to maintaining high standards of product quality, data integrity, regulatory compliance, and operational performance across its global network.
Facility Highlights
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Location:
Nottingham, UK
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Core Expertise:
Formulation development, spray drying and oral solid dose development, small scale commercial manufacture
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Development
Capabilities:Formulation screening, process development, analytical development, material characterization and clinical supply
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Manufacturing
Capabilities:Development-scale spray drying, clinical manufacturing and small-scale commercial manufacturing for oral dosage forms
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Specialist
Technologies:Amorphous solid dispersions, bioavailability enhancement and oral solid dosage forms
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Site Experience:
More than 20 years of material characterization, formulation development, spray drying and oral solid dose expertise
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Integrated UK
Network:Development and clinical capabilities at Nottingham connected with commercial-scale spray drying at Haverhill
Talk to Our Formulation Scientists
Whether you are assessing a poorly soluble compound, developing an amorphous solid dispersion, preparing clinical supply or planning for commercial scale-up, our formulation scientists can help define the right development pathway.
Speak with our Nottingham team about your molecule, programme stage and technical requirements.
Discover Codis
Explore how Codis applies its expertise in spray drying, microencapsulation, continuous granulation, final dosage forms, and functional products to meet your formulation and manufacturing needs.
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Commercial Spray Drying
Full lifecycle, development, and production expertise for high-volume commercial aqueous spray drying.
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Codis Amorphous Solid Dispersion (ASD)
Industry-leading know-how to design, scale, and manufacture amorphous solid dispersions for improved bioavailability of poorly soluble compounds.
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Microencapsulation
Proprietary microencapsulation processes to improve taste, odor masking, stability, or release profile.
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Continuous Granulation
Continuous high-shear granulation to improve flow, compressibility and disintegration.
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Organic & Polymer Chemistry
Advanced organic synthesis and polymer engineering, enabling robust, scalable manufacturing.
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Analytical Services
State-of-the-art instrumentation combined with data-science–driven PAT to provide method development, validation, release, and stability testing services.
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Final Dosage Forms
Leading global experts in direct compression and two-piece encapsulation products for vitamin, mineral and supplement markets.
Codis Insights & Updates
Stay current with the latest in particle engineering science and Codis articles and resources.
Connect with us to explore how our particle engineering, commercial spray drying, formulation, and advanced manufacturing capabilities deliver high-quality, dependable supply for even the most challenging products.