Organic & Polymer Chemistry
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High-Volume Continuous Industrial Flow Chemistry
Codis combines decades of process engineering experience with advanced flow chemistry expertise to deliver scalable, efficient, and safe continuous manufacturing. Our high-volume systems enable precise reaction control, faster optimization, and cleaner, higher-yielding processes, enabling consistent quality and sustainable production at commercial scale. Central to these capabilities are our LIST twin-shaft continuous kneader-reactors, integrated into our pilot and commercial-scale production plants. These reactors offer exceptional mixing and kneading behavior, effective self-cleaning properties, and efficient renewal of reaction boundary layers while maintaining low shear for high-viscosity, difficult-to-mix reactants and products.
Increase product quality and yield
More precise control of key reaction parameters such as mixing, heating, and residence time leads to better product yield and impurity control
Rapid analysis, optimization, and scale-up of chemical reactions
Testing a range of reaction variables is faster in flow processes and uses less substrate and reagent. Real-time analysis provides immediate feedback on the effect each variable has on reaction performance
Modular, customizable workflow
Flow chemistry equipment is highly modular, making it easy to configure equipment to meet the requirements of specific reactions
Improved process safety
Flow chemistry makes it significantly safer to handle hazardous or corrosive reagents and perform potentially dangerous reactions
Pilot- and Commercial-Scale Production
Codis scales chemical processes from lab to large-scale commercial production with efficiency. Two state-of-the-art plants use cutting-edge flow chemistry for synthesis and purification, seamlessly integrating with spray drying for final isolation. Sustainability drives our operations, with proven success in implementing green, efficient, and resource-conscious manufacturing processes.
End-to-End Chemistry Support
From early material design and feasibility studies through scale-up and commercial production, Codis integrates organic and polymer chemistry into every stage of the development lifecycle. Whether you require a custom polymer, excipient or API, we have the chemistry expertise and facilities that delivers commercial success.
Contact UsDiscover Codis
Explore how Codis applies its expertise in spray drying, microencapsulation, continuous granulation, final dosage forms, and functional products to meet your formulation and manufacturing needs.
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Commercial Spray Drying
Full lifecycle, development, and production expertise for high-volume commercial aqueous spray drying.
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Codis Amorphous Solid Dispersion (ASD)
Industry-leading know-how to design, scale, and manufacture amorphous solid dispersions for improved bioavailability of poorly soluble compounds.
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Microencapsulation
Proprietary microencapsulation processes to improve taste, odor masking, stability, or release profile.
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Continuous Granulation
Continuous high-shear granulation to improve flow, compressibility and disintegration.
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Organic & Polymer Chemistry
Advanced organic synthesis and polymer engineering, enabling robust, scalable manufacturing.
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Analytical Services
State-of-the-art instrumentation combined with data-science–driven PAT to provide method development, validation, release, and stability testing services.
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Final Dosage Forms
Leading global experts in direct compression and two-piece encapsulation products for vitamin, mineral and supplement markets.
Codis Insights & Updates
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Connect with us to explore how our particle engineering, commercial spray drying, formulation, and advanced manufacturing capabilities deliver high-quality, dependable supply for even the most challenging products.