Destab™
Why Destab™?
Engineered Particles for Optimal Oral Solid Dose Performance
Destab™ calcium and magnesium carbonate products are specifically engineered to deliver high functionality and streamlined performance in oral solid dose (OSD) manufacturing:
Coprocessed Granules
Synergistic interaction of binder and minerals results in excellent compressibility and disintegration
Enhanced Flow
Increased tableting speeds and improved yield for direct compression blends
Multiple Binder Options
Available in starch, acacia, and maltodextrin binders, supporting versatile formulation needs including chewable tablets and orally disintegrating tablets (ODTs)
Destab™ Product Line:
Co-Spray Dried Directly Compressible Minerals
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Destab™ Calcium Carbonate 90S Ultra 250 USP/EP
Coprocessed with a starch binder for optimized flow and compressibility.
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Destab™ Calcium Carbonate 90SE Ultra 250 USP/EP
Primarily targeting the EU market, this premium-grade granulation with starch binder delivers exceptional compressibility.
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Destab™ Calcium Carbonate 90A Ultra 250 USP/EP
Co-spray dried with an acacia binder for excellent flow characteristics.
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Destab™ Calcium Carbonate 95S Ultra 250 USP/EP
A higher potency formula with starch binder allows for smaller, easier-to-swallow tablets.
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Destab™ Calcium Carbonate 95AHD Ultra 250 USP/EP
High shear granulated with acacia to improve flow, this high-density product is ideal for smaller tablet formats.
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Destab™ Calcium Carbonate 95MD Ultra 250 USP/EP
A maltodextrin-based formula delivering a smooth texture ideal for chewables and ODTs.
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Destab™ Magnesium Carbonate 90S Ultra 250 USP/EP
Primarily serving the EU market, this starch-based binder provides superior compressibility.
Built for Quality and Compliance
Codis ensures every Destab™ product meets rigorous GMP and regulatory standards, with production processes aligned to ICH Q7, 21 CFR 210/211, and EU GMP regulations. In fact, we have exemplary audit record with global regulatory compliance, including US FDA and EU EudraLex standards.
Applications and Markets
Destab™ is engineered for high-performance formulation across various markets:
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Reliable compression and flow for tablets and capsules.
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Ideal for functional supplements requiring high mineral content and consistent delivery.
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Enhanced chewability and taste masking in chewables and orally disintegrating formats.
Discover Codis
Explore how Codis applies its expertise in spray drying, microencapsulation, continuous granulation, final dosage forms, and functional products to meet your formulation and manufacturing needs.
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Commercial Spray Drying
Full lifecycle, development, and production expertise for high-volume commercial aqueous spray drying.
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Codis Amorphous Solid Dispersion (ASD)
Industry-leading know-how to design, scale, and manufacture amorphous solid dispersions for improved bioavailability of poorly soluble compounds.
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Microencapsulation
Proprietary microencapsulation processes to improve taste, odor masking, stability, or release profile.
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Continuous Granulation
Continuous high-shear granulation to improve flow, compressibility and disintegration.
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Organic & Polymer Chemistry
Advanced organic synthesis and polymer engineering, enabling robust, scalable manufacturing.
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Analytical Services
State-of-the-art instrumentation combined with data-science–driven PAT to provide method development, validation, release, and stability testing services.
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Final Dosage Forms
Leading global experts in direct compression and two-piece encapsulation products for vitamin, mineral and supplement markets.
Codis Insights & Updates
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Connect with us to explore how our particle engineering, commercial spray drying, formulation, and advanced manufacturing capabilities deliver high-quality, dependable supply for even the most challenging products.