Sevelamer API
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Why Sevelamer from Codis?
Global Expertise in the Production of Sevelamer Hydrochloride & Sevelamer Carbonate
Clients across the globe turn to Codis to produce Sevelamer API thanks to our:
Unmatched Manufacturing Experience
Sevelamer was first manufactured at Haverhill in 1999 following its invention by GelTex. Today, Codis Haverhill remains the most experienced and specialized Sevelamer manufacturer in the world.
Dedicated API Production Facilities
Two purpose-built production buildings are exclusively devoted to the production of Sevelamer Hydrochloride and Sevelamer Carbonate, ensuring focus, consistency, and scale.
Proprietary Technology
Codis uses exclusive manufacturing technologies not available to other producers, delivering superior quality, safety, and performance.
Advantages of the Codis Manufacturing Process
At Codis Haverhill, Sevelamer production is carried out using a fully continuous manufacturing process that eliminates batch-to-batch variability, enhancing both product quality and throughput. Real-time process analytical technology (PAT) provides exceptional control and consistency throughout every run, ensuring uniformity across all production lots. This consistency translates directly to improved tabletability and reliable drug product performance for downstream manufacturers.
In addition to technical excellence, our process is environmentally responsible, significantly reducing the volume of organic solvents needed and recovering up to 75% of the water used during production. The result is a high-performing, sustainable process that supports both patient safety and environmental stewardship.
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PAT
Real-time process analytical technology provides exceptional control
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Consistency
throughout every run, ensuring uniformity across all production lots
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75%
of the water used during production is recovered
Built for Regulatory Confidence
Over Two Decades of Quality Excellence
The Haverhill site has a robust compliance history with US and EU regulatory agencies, backed by a legacy of large pharma quality management systems.
Global Supply Capability
With commercial-scale capacity of 100’s of metric tons annually, and export-ready operations, Codis delivers high-quality Sevelamer APIs to pharmaceutical manufacturers worldwide.
Discover Codis
Explore how Codis applies its expertise in spray drying, microencapsulation, continuous granulation, final dosage forms, and functional products to meet your formulation and manufacturing needs.
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Commercial Spray Drying
Full lifecycle, development, and production expertise for high-volume commercial aqueous spray drying.
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Codis Amorphous Solid Dispersion (ASD)
Industry-leading know-how to design, scale, and manufacture amorphous solid dispersions for improved bioavailability of poorly soluble compounds.
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Microencapsulation
Proprietary microencapsulation processes to improve taste, odor masking, stability, or release profile.
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Continuous Granulation
Continuous high-shear granulation to improve flow, compressibility and disintegration.
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Organic & Polymer Chemistry
Advanced organic synthesis and polymer engineering, enabling robust, scalable manufacturing.
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Analytical Services
State-of-the-art instrumentation combined with data-science–driven PAT to provide method development, validation, release, and stability testing services.
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Final Dosage Forms
Leading global experts in direct compression and two-piece encapsulation products for vitamin, mineral and supplement markets.
Codis Insights & Updates
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Connect with us to explore how our particle engineering, commercial spray drying, formulation, and advanced manufacturing capabilities deliver high-quality, dependable supply for even the most challenging products.